How Can I Take Down Big Daddies?
I'm at the beginning of the game on Normal, and am currently finding fighting the Big Daddies to be a bit challenging. As in I wasted half a clip of Machine Gun Ammo and 3 EVE Hypos taking down the ones in the Medical Bay, and I'm now being toasted in Neptune's Bounty.
Should I just wait till later in the game, or are there tips for defeating the Daddies?
The most important thing to remember is that as long as the Big Daddy is mobile with a line of sight on you, you are in mortal danger.
The trick to bringing down a Big Daddy is to use whatever means possible to immobilize him. There are various tools you can use to impede his movement, or attacks, and you're going to need to learn to use all of them if you want to bring down Big Daddies repeatedly.
Some of the best ones to use are as follows:
Ice Plasmid Freezing a Big Daddy on the spot can give you a chance to get to cover, but also makes it harder to damage them while frozen.
Hacked Turrets A friendly turret won't put up a fight for very long against a Big Daddy, but it may give you the time you need to get to cover.
Bee Arms The Bee Arms are one of the best weapons to use against a Big Daddy. For periods at a time after being unleashed, your bees will swarm the Big Daddy, causing him to stumble around waving his arms in the air. Higher level Bee Arms will disorient the Big Daddy for longer periods, as well as deal more damage to him over time.
Electricity Stun While not as effective (in my opinion) as the bee arms, this plasmid is available fairly early in the game (as @Ender pointed out), and can be very useful for immobilizing Big Daddies when you need to get to cover.
Shotgun (Point Blank) A shotgun blast at point blank range will stun the Big Daddy for a short period of time; do this repeatedly to deal a ton of damage quickly, then use one of the above techniques to escape. Using Electric rounds for your Shotgun will extend this stun period substantially.
Trap Bolts These are pretty self-explanatory. Just use them in doorways and suchlike before getting on a Big Daddy's bad side, then get him to run through them. These do a ton of damage, though ammo is rare.
Another Big Daddy No, you're not crazy. Sometimes, getting two Daddies to fight one another is a viable option for bringing the one you initially attacked down to size, but this isn't always easy to achieve, nor is it usually terribly safe.
Of note is the fact that if you pick up a dead Rosie type Big Daddy using telekinesis, it will slowly rotate to upside-down, and you can then stand it on its head with its legs hanging out to the sides. I went on a Big Daddy killing spree in one section and got a gallery of about six of them posed this way. Then one of the character models 'broke' somehow, and kind of melted into a puddle of boneless Big Daddy. It was great.